Trial literature on tumours of the central nervous system (CNS)

Literature on trials concerning medulloblastoma and other CNS-PNET, pineoblastoma, ependymoma, low-grade glioma, high-grade glioma, choroid plexus tumours, and craniopharyngioma

Last modification: 2024/05/03 https://kinderkrebsinfo.de/doi/e123830

Medulloblastoma

Trial literature on medulloblastoma

Pubmed

  1. Sabel M, Fleischhack G, Tippelt S, Gustafsson G, Doz F, Kortmann R, Massimino M, Navajas A, von Hoff K, Rutkowski S, Warmuth-Metz M, Clifford SC, Pietsch T, Pizer B, Lannering B, SIOP-E Brain Tumour Group: Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4 study. Journal of neuro-oncology 2016, [PMID: 27423645] SAB2016
  2. Friedrich C, Warmuth-Metz M, von Bueren AO, Nowak J, Bison B, von Hoff K, Pietsch T, Kortmann RD, Rutkowski S: Primitive neuroectodermal tumors of the brainstem in children treated according to the HIT trials: clinical findings of a rare disease. Journal of neurosurgery. Pediatrics 2015, 1 [PMID: 25555122] FRI2015
  3. Ottensmeier H, Zimolong B, Wolff JE, Ehrich J, Galley N, von Hoff K, Kuehl J, Rutkowski S: Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours. European journal of paediatric neurology 2015, Epub ahead of print [PMID: 25617910] OTT2015
  4. Gerber NU, Mynarek M, von Hoff K, Friedrich C, Resch A, Rutkowski S: Recent developments and current concepts in medulloblastoma. Cancer treatment reviews 2014, 40: 356 [PMID: 24389035] GER2014a
  5. Bode U, Zimmermann M, Moser O, Rutkowski S, Warmuth-Metz M, Pietsch T, Kortmann RD, Faldum A, Fleischhack G: Treatment of recurrent primitive neuroectodermal tumors (PNET) in children and adolescents with high-dose chemotherapy (HDC) and stem cell support: results of the HITREZ 97 multicentre trial. Journal of neuro-oncology 2014, 120: 635 [PMID: 25179451] BOD2014
  6. Kennedy C, Bull K, Chevignard M, Culliford D, Dörr HG, Doz F, Kortmann RD, Lannering B, Massimino M, Navajas Gutiérrez A, Rutkowski S, Spoudeas HA, Calaminus G, PNET4 study group of the Brain Tumour Group of The European branch of the International Society of Paediatric Oncology (SIOP-E): Quality of survival and growth in children and young adults in the PNET4 European controlled trial of hyperfractionated versus conventional radiation therapy for standard-risk medulloblastoma. International journal of radiation oncology, biology, physics 2014, 88: 292 [PMID: 24239386] KEN2014
  7. Gessi M, von Bueren AO, Treszl A, Mühlen AZ, Hartmann W, Warmuth-Metz M, Rutkowski S, Pietsch T: MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system. Neuro-oncology 2014, [PMID: 24470553] GES2014
  8. Nowak J, Seidel C, Pietsch T, Friedrich C, von Hoff K, Rutkowski S, Warmuth-Metz M: Ependymoblastoma of the brainstem: MRI findings and differential diagnosis. Pediatric blood & cancer 2014, 61: 1132 [PMID: 24464920] NOW2014
  9. Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones DT, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott PA, von Hoff K, von Bueren AO, Friedrich C, Mynarek M, Skladny H, Fleischhack G, Taylor MD, Cremer F, Lichter P, Faldum A, Reifenberger G, Rutkowski S, Pfister SM: Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort. Acta neuropathologica 2014, 128: 137 [PMID: 24791927] PIE2014
  10. Goschzik T, Zur Mühlen A, Kristiansen G, Haberler C, Stefanits H, Friedrich C, von Hoff K, Rutkowski S, Pfister SM, Pietsch T: Molecular stratification of medulloblastoma: Comparison of histological and genetic methods to detect Wnt activated tumors. Neuropathology and applied neurobiology 2014, [PMID: 24894640] GOS2014
  11. Gerber NU, von Hoff K, Resch A, Ottensmeier H, Kwiecien R, Faldum A, Matuschek C, Hornung D, Bremer M, Benesch M, Pietsch T, Warmuth-Metz M, Kuehl J, Rutkowski S, Kortmann RD: Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy. International journal of radiation oncology, biology, physics 2014, 89: 863 [PMID: 24969797] GER2014
  12. Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren AO, Kordes U: Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression. Journal of neuro-oncology 2013, 112: 191 [PMID: 23371454] HAG2013
  13. Remke M, Hering E, Gerber NU, Kool M, Sturm D, Rickert CH, Gerß J, Schulz S, Hielscher T, Hasselblatt M, Jeibmann A, Hans V, Ramaswamy V, Taylor MD, Pietsch T, Rutkowski S, Korshunov A, Monoranu CM, Frühwald MC: Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma. Child's nervous system 2013, 29: 1253 [PMID: 23677175] REM2013
  14. Friedrich C, von Bueren AO, von Hoff K, Gerber NU, Ottensmeier H, Deinlein F, Benesch M, Kwiecien R, Pietsch T, Warmuth-Metz M, Faldum A, Kuehl J, Kortmann RD, Rutkowski S: Treatment of young children with CNS-primitive neuroectodermal tumors/pineoblastomas in the prospective multicenter trial HIT 2000 using different chemotherapy regimens and radiotherapy. Neuro-oncology 2013, 15: 224 [PMID: 23223339] FRI2013
  15. von Bueren AO, Bacolod MD, Hagel C, Heinimann K, Fedier A, Kordes U, Pietsch T, Koster J, Grotzer MA, Friedman HS, Marra G, Kool M, Rutkowski S: Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. British journal of cancer 2012, 107: 1399-408 [PMID: 22976800] BUE2012
  16. Lannering B, Rutkowski S, Doz F, Pizer B, Gustafsson G, Navajas A, Massimino M, Reddingius R, Benesch M, Carrie C, Taylor R, Gandola L, Björk-Eriksson T, Giralt J, Oldenburger F, Pietsch T, Figarella-Branger D, Robson K, Forni M, Clifford SC, Warmuth-Metz M, von Hoff K, Faldum A, Mosseri V, Kortmann R: Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: results from the randomized multicenter HIT-SIOP PNET 4 trial. Journal of clinical oncology 2012 Sep 10; 30: 3187 [PMID: 22851561] LAN2012
  17. Müller K, Zwiener I, Welker H, Maaß E, Bongartz R, Berthold F, Pietsch T, Warmuth-Metz M, von Bueren A, Rutkowski S: Curative treatment for central nervous system medulloepithelioma despite residual disease after resection : Report of two cases treated according to the GPHO protocol HIT 2000 and review of the literature. Strahlentherapie und Onkologie 2011,Epub ahead of print [PMID: 22037651] MUE2011b
  18. Gerber NU, von Hoff K, von Bueren AO, Treulieb W, Deinlein F, Benesch M, Zwiener I, Soerensen N, Warmuth-Metz M, Pietsch T, Mittler U, Kuehl J, Kortmann RD, Grotzer MA, Rutkowski S: A long duration of the prediagnostic symptomatic interval is not associated with an unfavourable prognosis in childhood medulloblastoma. European journal of cancer 2011, [Epub ahead of print] [PMID: 22153558] GER2011a
  19. von Bueren AO, von Hoff K, Pietsch T, Gerber NU, Warmuth-Metz M, Deinlein F, Zwiener I, Faldum A, Fleischhack G, Benesch M, Krauss J, Kuehl J, Kortmann RD, Rutkowski S: Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology. Neuro Oncol 2011, 13: 669 [PMID: 21636711] BUE2011a
  20. von Bueren AO, von Hoff K, Pietsch T, Gerber NU, Warmuth-Metz M, Deinlein F, Zwiener I, Faldum A, Fleischhack G, Benesch M, Krauss J, Kuehl J, Kortmann RD, Rutkowski S: Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology. Neuro-oncology 2011, 13: 669 [PMID: 21636711] BUE2011
  21. Gerber NU, von Hoff K, von Bueren AO, Treulieb W, Warmuth-Metz M, Pietsch T, Soerensen N, Faldum A, Emser A, Schlegel PG, Deinlein F, Kortmann RD, Rutkowski S: Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006. J Neurooncol 2011, 102: 459 [PMID: 21308398] GER2011
  22. Seifert G, Kanitz JL, Pretzer K, Henze G, Witt K, Reulecke S, Voss A: Improvement of Heart Rate Variability by Eurythmy Therapy After a 6-Week Eurythmy Therapy Training. Integr Cancer Ther 2011, [Epub ahead of print] [PMID: 21733984] SEI2011
  23. Seifert G, Rutkowski S, Jesse P, Madeleyn R, Reif M, Henze G, Längler A: 2. Anthroposophic Supportive Treatment in Children With Medulloblastoma Receiving First-line Therapy. J Pediatr Hematol Oncol 2011, Epub ahead of print [PMID: 21368673] SEI2011
  24. von Bueren AO, Warmuth-Metz M, Schlegel PG, Soerensen N, Krauss J, Roggendorf W, Pietsch T, Feiden W, Graf N, Pohl F, Flentje M, Kuehl J, Rutkowski S: Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses. Pediatr Blood Cancer 2011, 56: 503 [PMID: 21113945] BUE2011
  25. Rutkowski S, Cohen B, Finlay J, Luksch R, Ridola V, Valteau-Couanet D, Hara J, Garre ML, Grill J: Medulloblastoma in young children. Pediatr Blood Cancer 2010, 54: 635 [PMID: 20146217] RUT2010b
  26. Benesch M, Weber-Mzell D, Gerber NU, von Hoff K, Deinlein F, Krauss J, Warmuth-Metz M, Kortmann RD, Pietsch T, Driever PH, Quehenberger F, Urban C, Rutkowski S: Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database. J Neurosurg Pediatr 2010, 6: 137 [PMID: 20672934] BEN2010a
  27. Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, Giangaspero F, Ellison DW, Garre ML, Biassoni V, Grundy RG, Finlay JL, Dhall G, Raquin MA, Grill J: Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. J Clin Oncol 2010, 28: 4961 [PMID: 20940197] RUT2010a
  28. Warmuth-Metz M, Blashofer S, von Bueren AO, von Hoff K, Bison B, Pohl F, Kortmann RD, Pietsch T, Rutkowski S: Recurrence in childhood medulloblastoma. J Neurooncol 2010, Epub ahead of print] [PMID: 21069427] WAR2010
  29. Massimino M, Giangaspero F, Garrè ML, Gandola L, Poggi G, Biassoni V, Gatta G, Rutkowski S: Childhood medulloblastoma. Crit Rev Oncol Hematol 2010, Epub ahead of print [PMID: 21129995] MAS2010
  30. Benesch M, Sperl D, von Bueren AO, Schmid I, von Hoff K, Warmuth-Metz M, Ferrari R, Lassay L, Kortmann RD, Pietsch T, Rutkowski S: Primary central nervous system primitive neuroectodermal tumors (CNS-PNETs) of the spinal cord in children: four cases from the German HIT database with a critical review of the literature. J Neurooncol 2010, Epub ahead of print [PMID: 21181235] BEN2010
  31. Ardon H, De Vleeschouwer S, Van Calenbergh F, Claes L, Kramm CM, Rutkowski S, Wolff JE, Van Gool SW: Adjuvant dendritic cell-based tumour vaccination for children with malignant brain tumours. Pediatric blood & cancer 2010, 54: 519 [PMID: 19852061] ARD2010
  32. von Hoff K, Hartmann W, von Bueren AO, Gerber NU, Grotzer MA, Pietsch T, Rutkowski S: Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors. Pediatric blood & cancer 2010, 54: 369 [PMID: 19908297] HOF2010
  33. Rutkowski S, Gerber NU, von Hoff K, Gnekow A, Bode U, Graf N, Berthold F, Henze G, Wolff JE, Warmuth-Metz M, Soerensen N, Emser A, Ottensmeier H, Deinlein F, Schlegel PG, Kortmann RD, Pietsch T, Kuehl J, German Pediatric Brain Tumor Study Group: Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy. Neuro-oncology 2009, 11: 201 [PMID: 18818397] RUT2009a
  34. Benesch M, Siegler N, Hoff K, Lassay L, Kropshofer G, Müller H, Sommer C, Rutkowski S, Fleischhack G, Urban C: Safety and toxicity of intrathecal liposomal cytarabine (Depocyte) in children and adolescents with recurrent or refractory brain tumors: a multi-institutional retrospective study. Anti-cancer drugs 2009, 20: 794 [PMID: 19617818] BEN2009a
  35. Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Gerber NU, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A: Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. Journal of clinical oncology 2009, 27: 1627 [PMID: 19255330] PFI2009
  36. von Hoff K, Hinkes B, Gerber NU, Deinlein F, Mittler U, Urban C, Benesch M, Warmuth-Metz M, Soerensen N, Zwiener I, Goette H, Schlegel PG, Pietsch T, Kortmann RD, Kuehl J, Rutkowski S: Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91. European journal of cancer (Oxford, England : 1990) 2009, 45: 1209 [PMID: 19250820] HOF2009
  37. Rutkowski S, Riehle E: Access to employment and economic independence in cerebral palsy. Physical medicine and rehabilitation clinics of North America 2009, 20: 535 [PMID: 19643352] RUT2009
  38. von Bueren AO, von Hoff K, Benesch M, Rutkowski S: Dose reductions of vincristine in children with medulloblastoma treated in the maintenance arm of the prospective multicenter trial HIT'91. Klinische Padiatrie 2009, 221: 396 [PMID: 19890797] BUE2009
  39. Rutkowski S, von Bueren A, von Hoff K, Hartmann W, Shalaby T, Deinlein F, Warmuth-Metz M, Soerensen N, Emser A, Bode U, Mittler U, Urban C, Benesch M, Kortmann RD, Schlegel PG, Kuehl J, Pietsch T, Grotzer M: Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91. Clinical cancer research 2007, 13: 2651 [PMID: 17473196] RUT2007a
  40. Rutkowski S: Timely identification of suspected paediatric CNS tumours. The lancet oncology 2007, 8: 664 [PMID: 17679075] RUT2007
  41. Grotzer MA, von Hoff K, von Bueren AO, Shalaby T, Hartmann W, Warmuth-Metz M, Emser A, Kortmann RD, Kuehl J, Pietsch T, Rutkowski S: Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91--implications for investigating childhood medulloblastoma. Klinische Padiatrie 2007, 219: 312 [PMID: 18050040] GRO2007
  42. Timmermann B, Kortmann RD, Kühl J, Rutkowski S, Meisner C, Pietsch T, Deinlein F, Urban C, Warmuth-Metz M, Bamberg M: Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials. Journal of clinical oncology 2006, 24: 1554 [PMID: 16575007] TIM2006
  43. Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth-Metz M, Soerensen N, Graf N, Emser A, Pietsch T, Wolff JE, Kortmann RD, Kuehl J: Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. The New England journal of medicine 2005, 352: 978 [PMID: 15758008] RUT2005
  44. Timmermann B, Kortmann RD, Kühl J, Rutkowski S, Dieckmann K, Meisner C, Bamberg M: Role of radiotherapy in anaplastic ependymoma in children under age of 3 years: results of the prospective German brain tumor trials HIT-SKK 87 and 92. Radiotherapy and oncology 2005, 77: 278 [PMID: 16300848] TIM2005
  45. Kortmann RD, Timmermann B, Rutkowski S, Bamberg M: Re: B. Beuthien-Baumann, et al. Differentiation between recurrent tumor and radiation necrosis in a child with anaplastic ependymoma after chemotherapy and radiation therapy. Strahlenther Onkol 2003;179:819-22. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 2004, 180: 245 [PMID: 15057436] KOR2004a
  46. Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sörensen N, Kühl J: Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998, 16: 2478 [PMID: 9667267] SCH1998m
  47. Scheurlen W, Kühl J: Current diagnostic and therapeutic management of CNS metastasis in childhood primitive neuroectodermal tumors and ependymomas. Journal of neuro-oncology 1998, 38(2-3): 181 [PMID: 9696369] SCH1998l
  48. Scheurlen WG, Seranski P, Mincheva A, Kühl J, Sörensen N, Krauss J, Lichter P, Poustka A, Wilgenbus KK: High-resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11. 2. Genes, chromosomes & cancer 1997, 18: 50 [PMID: 8993980] SCH1997k

Ependymoma

Trial literature on ependymoma

Pubmed

  1. Obrecht D, Mynarek M, Stickan-Verfürth M, Bison B, Schüller U, Pajtler K, Hagel C, Thomale UW, Fleischhack G, Timmermann B, Rutkowski S: [Pediatric Intracranial Ependymoma - Recommendations for First-Line Treatment from the German HIT-MED study group]. Klinische Padiatrie 2023, 235: 167 [PMID: 37172610] OBR2023
  2. Peters S, Merta J, Schmidt L, Jazmati D, Kramer PH, Blase C, Tippelt S, Fleischhack G, Stock A, Bison B, Rutkowski S, Pietsch T, Kortmann RD, Timmermann B: Evaluation of dose, volume, and outcome in children with localized, intracranial ependymoma treated with proton therapy within the prospective KiProReg Study. Neuro-oncology 2022, 24: 1193 [PMID: 34964901] PET2022b
  3. Adolph JE, Fleischhack G, Gaab C, Mikasch R, Mynarek M, Rutkowski S, Schüller U, Pfister SM, Pajtler KW, Milde T, Witt O, Bison B, Warmuth-Metz M, Kortmann RD, Dietzsch S, Pietsch T, Timmermann B, Tippelt S, German GPOH HIT-Network: Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies. Journal of neuro-oncology 2021, 155: 193 [PMID: 34657224] ADO2021a
  4. Zschernack V, Jünger ST, Mynarek M, Rutkowski S, Garre ML, Ebinger M, Neu M, Faber J, Erdlenbruch B, Claviez A, Bielack S, Brozou T, Frühwald MC, Dörner E, Dreschmann V, Stock A, Solymosi L, Hench J, Frank S, Vokuhl C, Waha A, Andreiuolo F, Pietsch T: Supratentorial ependymoma in childhood: more than just RELA or YAP. Acta neuropathologica 2021, 141: 455 [PMID: 33481105] ZSC2021
  5. Kresbach C, Dorostkar MM, Suwala AK, Wefers AK, Schweizer L, Engertsberger L, Bison B, Mynarek M, Kloth-Stachnau K, Spohn M, von Deimling A, Benesch M, Hagel C, Mautner VF, Rutkowski S, Schüller U: Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype. Acta neuropathologica 2021, 141: 971 [PMID: 33844070] KRE2021
  6. Adolph JE, Fleischhack G, Mikasch R, Zeller J, Warmuth-Metz M, Bison B, Mynarek M, Rutkowski S, Schüller U, von Hoff K, Obrecht D, Pietsch T, Pfister SM, Pajtler KW, Witt O, Witt H, Kortmann RD, Timmermann B, Krauß J, Frühwald MC, Faldum A, Kwiecien R, Bode U, Tippelt S: Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study. Neuro-oncology 2021, 23: 1012 [PMID: 33331885] ADO2021
  7. Jünger ST, Andreiuolo F, Mynarek M, Dörner E, Zur Mühlen A, Rutkowski S, von Bueren AO, Pietsch T: Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome. ChNS 2020, 36: 2693 [PMID: 32474813] JUE2020a
  8. Neumann JE, Spohn M, Obrecht D, Mynarek M, Thomas C, Hasselblatt M, Dorostkar MM, Wefers AK, Frank S, Monoranu CM, Koch A, Witt H, Kool M, Pajtler KW, Rutkowski S, Glatzel M, Schüller U: Molecular characterization of histopathological ependymoma variants. Acta neuropathologica 2020, 139: 305 [PMID: 31679042] NEU2020
  9. Ottensmeier H, Schlegel PG, Eyrich M, Wolff JE, Juhnke BO, von Hoff K, Frahsek S, Schmidt R, Faldum A, Fleischhack G, von Bueren A, Friedrich C, Resch A, Warmuth-Metz M, Krauss J, Kortmann RD, Bode U, Kühl J, Rutkowski S: Treatment of children under 4 years of age with medulloblastoma and ependymoma in the HIT2000/HIT-REZ 2005 trials: Neuropsychological outcome 5 years after treatment. PloS one 2020, 15:e0227693 [PMID: 31971950] OTT2020
  10. Jünger ST, Andreiuolo F, Mynarek M, Wohlers I, Rahmann S, Klein-Hitpass L, Dörner E, Zur Mühlen A, Velez-Char N, von Hoff K, Warmuth-Metz M, Kortmann RD, Timmermann B, von Bueren A, Rutkowski S, Pietsch T: CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort. Acta neuropathologica 2020, 140: 405 [PMID: 32514758] JUE2020
  11. Scholtes C, Baust K, Weinhold L, Creutzig U, Gnekow A, Hinz A, Kaatsch P, Kreitz K, Langer T, Rutkowski S, Singer S, Spix C, Teske C, Schmid M, Dilloo D, Calaminus G: Health status, health-related quality of life, and socioeconomic outcome in childhood brain tumor survivors: a German cohort study. Neuro-oncology 2019, 21: 1069 [PMID: 30793186] SCH2019a
  12. Nowak J, Jünger ST, Huflage H, Seidel C, Hohm A, Vandergrift LA, von Hoff K, Rutkowski S, Pietsch T, Warmuth-Metz M: MRI Phenotype of RELA-fused Pediatric Supratentorial Ependymoma. Clinical neuroradiology 2019, 29: 595 [PMID: 30027327] NOW2019
  13. Benesch M, Mynarek M, Witt H, Warmuth-Metz M, Pietsch T, Bison B, Pfister SM, Pajtler KW, Kool M, Schüller U, Pietschmann K, Juhnke BO, Tippelt S, Fleischhack G, Schmid I, Kramm CM, Vorwerk P, Beilken A, Classen CF, Hernáiz Driever P, Kropshofer G, Imschweiler T, Lemmer A, Kortmann RD, Rutkowski S, von Hoff K: Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series. The oncologist 2019, 24:e921-e929 [PMID: 30850560] BEN2019
  14. Jünger ST, Mynarek M, Wohlers I, Dörner E, Mühlen AZ, Velez-Char N, von Hoff K, Rutkowski S, Warmuth-Metz M, Kortmann RD, Timmermann B, Rahmann S, Klein-Hitpass L, von Bueren AO, Pietsch T: Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort. Acta neuropathologica communications 2019, 7: 181 [PMID: 31727173] JUE2019
  15. Andreiuolo F, Le Teuff G, Bayar MA, Kilday JP, Pietsch T, von Bueren AO, Witt H, Korshunov A, Modena P, Pfister SM, Pagès M, Castel D, Giangaspero F, Chimelli L, Varlet P, Rutkowski S, Frappaz D, Massimino M, Grundy R, Grill J, SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents): Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification. PloS one 2017, 12:e0178351 [PMID: 28617804] AND2017
  16. Pajtler KW, Tippelt S, Siegler N, Reichling S, Zimmermann M, Mikasch R, Bode U, Gnekow A, Pietsch T, Benesch M, Rutkowski S, Fleischhack G: Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumors. Journal of neuro-oncology 2016, 128: 463 [PMID: 27147083] PAJ2016
  17. Gessi M, Capper D, Sahm F, Huang K, von Deimling A, Tippelt S, Fleischhack G, Scherbaum D, Alfer J, Juhnke BO, von Hoff K, Rutkowski S, Warmuth-Metz M, Chavez L, Pfister SM, Pietsch T, Jones DT, Sturm D: Evidence of H3 K27M mutations in posterior fossa ependymomas. Acta neuropathologica 2016, 132: 635 [PMID: 27539613] GES2016
  18. Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, Lipp ES, Dunham C, Hukin J, Eisenstat DD, Fulton D, van Landeghem FK, Santi M, van Veelen ML, Van Meir EG, Osuka S, Fan X, Muraszko KM, Tirapelli DP, Oba-Shinjo SM, Marie SK, Carlotti CG, Lee JY, Rao AA, Giannini C, Faria CC, Nunes S, Mora J, Hamilton RL, Hauser P, Jabado N, Petrecca K, Jung S, Massimi L, Zollo M, Cinalli G, Bognár L, Klekner A, Hortobágyi T, Leary S, Ermoian RP, Olson JM, Leonard JR, Gardner C, Grajkowska WA, Chambless LB, Cain J, Eberhart CG, Ahsan S, Massimino M, Giangaspero F, Buttarelli FR, Packer RJ, Emery L, Yong WH, Soto H, Liau LM, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis MA, Zagzag D, Wheeler H, von Hoff K, Alonso MM, Tuñon T, Schüller U, Zitterbart K, Sterba J, Chan JA, Guzman M, Elbabaa SK, Colman H, Dhall G, Fisher PG, Fouladi M, Gajjar A, Goldman S, Hwang E, Kool M, Ladha H, Vera-Bolanos E, Wani K, Lieberman F, Mikkelsen T, Omuro AM, Pollack IF, Prados M, Robins HI, Soffietti R, Wu J, Metellus P, Tabori U, Bartels U, Bouffet E, Hawkins CE, Rutka JT, Dirks P, Pfister SM, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Ellison DW, Taylor MD: Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. Journal of clinical oncology 2016 Jul 20; 34: 2468 [PMID: 27269943] RAM2016
  19. Pajtler KW, Witt H, Sill M, Jones DT, Hovestadt V, Kratochwil F, Wani K, Tatevossian R, Punchihewa C, Johann P, Reimand J, Warnatz HJ, Ryzhova M, Mack S, Ramaswamy V, Capper D, Schweizer L, Sieber L, Wittmann A, Huang Z, van Sluis P, Volckmann R, Koster J, Versteeg R, Fults D, Toledano H, Avigad S, Hoffman LM, Donson AM, Foreman N, Hewer E, Zitterbart K, Gilbert M, Armstrong TS, Gupta N, Allen JC, Karajannis MA, Zagzag D, Hasselblatt M, Kulozik AE, Witt O, Collins VP, von Hoff K, Rutkowski S, Pietsch T, Bader G, Yaspo ML, von Deimling A, Lichter P, Taylor MD, Gilbertson R, Ellison DW, Aldape K, Korshunov A, Kool M, Pfister SM: Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. Cancer cell 2015, 27: 728 [PMID: 25965575] PAJ2015
  20. Nowak J, Seidel C, Pietsch T, Friedrich C, von Hoff K, Rutkowski S, Warmuth-Metz M: Ependymoblastoma of the brainstem: MRI findings and differential diagnosis. Pediatric blood & cancer 2014, 61: 1132 [PMID: 24464920] NOW2014
  21. Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren AO, Kordes U: Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression. Journal of neuro-oncology 2013, 112: 191 [PMID: 23371454] HAG2013
  22. Gerber NU, von Hoff K, von Bueren AO, Treulieb W, Warmuth-Metz M, Pietsch T, Soerensen N, Faldum A, Emser A, Schlegel PG, Deinlein F, Kortmann RD, Rutkowski S: Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006. J Neurooncol 2011, 102: 459 [PMID: 21308398] GER2011
  23. Benesch M, Weber-Mzell D, Gerber NU, von Hoff K, Deinlein F, Krauss J, Warmuth-Metz M, Kortmann RD, Pietsch T, Driever PH, Quehenberger F, Urban C, Rutkowski S: Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database. J Neurosurg Pediatr 2010, 6: 137 [PMID: 20672934] BEN2010a
  24. Timmermann B, Kortmann RD, Kühl J, Rutkowski S, Dieckmann K, Meisner C, Bamberg M: Role of radiotherapy in anaplastic ependymoma in children under age of 3 years: results of the prospective German brain tumor trials HIT-SKK 87 and 92. Radiotherapy and oncology 2005, 77: 278 [PMID: 16300848] TIM2005
  25. Kortmann RD, Timmermann B, Rutkowski S, Bamberg M: Re: B. Beuthien-Baumann, et al. Differentiation between recurrent tumor and radiation necrosis in a child with anaplastic ependymoma after chemotherapy and radiation therapy. Strahlenther Onkol 2003;179:819-22. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 2004, 180: 245 [PMID: 15057436] KOR2004a

Non-rhabdoid, embryonal CNS tumours (formerly CNS-PNET) and pineoblastoma

Trial literature on non-rhabdoid, embryonal CNS tumours (formerly CNS-PNET) and pineoblastoma

Pubmed

  1. Juhnke BO, Gessi M, Gerber NU, Friedrich C, Mynarek M, von Bueren AO, Haberler C, Schüller U, Kortmann RD, Timmermann B, Bison B, Warmuth-Metz M, Kwiecien R, Pfister SM, Spix C, Pietsch T, Kool M, Rutkowski S, von Hoff K: Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial. Neuro-oncology 2022, 24: 127 [PMID: 33908610] JUH2022
  2. von Hoff K, Haberler C, Schmitt-Hoffner F, Schepke E, de Rojas T, Jacobs S, Zapotocky M, Sumerauer D, Perek-Polnik M, Dufour C, van Vuurden D, Slavc I, Gojo J, Pickles JC, Gerber NU, Massimino M, Gil-da-Costa MJ, Garami M, Kumirova E, Sehested A, Scheie D, Cruz O, Moreno L, Cho J, Zeller B, Bovenschen N, Grotzer M, Alderete D, Snuderl M, Zheludkova O, Golanov A, Okonechnikov K, Mynarek M, Juhnke BO, Rutkowski S, Schüller U, Pizer B, von Zezschwitz B, Kwiecien R, Wechsung M, Konietschke F, Hwang EI, Sturm D, Pfister SM, von Deimling A, Rushing EJ, Ryzhova M, Hauser P, Łastowska M, Wesseling P, Giangaspero F, Hawkins C, Figarella-Branger D, Eberhart C, Burger P, Gessi M, Korshunov A, Jacques TS, Capper D, Pietsch T, Kool M: Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities: results of an international, retrospective study. Neuro-oncology 2021, 23: 1597 [PMID: 34077956] HOF2021
  3. Sievers P, Henneken SC, Blume C, Sill M, Schrimpf D, Stichel D, Okonechnikov K, Reuss DE, Benzel J, Maaß KK, Kool M, Sturm D, Zheng T, Ghasemi DR, Kohlhof-Meinecke P, Cruz O, Suñol M, Lavarino C, Ruf V, Boldt HB, Pagès M, Pouget C, Schweizer L, Kranendonk MEG, Akhtar N, Bunkowski S, Stadelmann C, Schüller U, Mueller WC, Dohmen H, Acker T, Harter PN, Mawrin C, Beschorner R, Brandner S, Snuderl M, Abdullaev Z, Aldape K, Gilbert MR, Armstrong TS, Ellison DW, Capper D, Ichimura K, Reifenberger G, Grundy RG, Jabado N, Krskova L, Zapotocky M, Vicha A, Varlet P, Wesseling P, Rutkowski S, Korshunov A, Wick W, Pfister SM, Jones DTW, von Deimling A, Pajtler KW, Sahm F: Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors. Acta neuropathologica 2021, 142: 827 [PMID: 34355256] SIE2021
  4. Pfaff E, Aichmüller C, Sill M, Stichel D, Snuderl M, Karajannis MA, Schuhmann MU, Schittenhelm J, Hasselblatt M, Thomas C, Korshunov A, Rhizova M, Wittmann A, Kaufhold A, Iskar M, Ketteler P, Lohmann D, Orr BA, Ellison DW, von Hoff K, Mynarek M, Rutkowski S, Sahm F, von Deimling A, Lichter P, Kool M, Zapatka M, Pfister SM, Jones DTW: Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations. Acta neuropathologica 2020, 139: 243 [PMID: 31768671] PFA2020
  5. Barz MJ, Hof J, Groeneveld-Krentz S, Loh JW, Szymansky A, Astrahantseff K, von Stackelberg A, Khiabanian H, Ferrando AA, Eckert C, Kirschner-Schwabe R: Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia. Blood 2020, 135: 921 [PMID: 31971569] BAR2020
  6. Scholtes C, Baust K, Weinhold L, Creutzig U, Gnekow A, Hinz A, Kaatsch P, Kreitz K, Langer T, Rutkowski S, Singer S, Spix C, Teske C, Schmid M, Dilloo D, Calaminus G: Health status, health-related quality of life, and socioeconomic outcome in childhood brain tumor survivors: a German cohort study. Neuro-oncology 2019, 21: 1069 [PMID: 30793186] SCH2019a
  7. Mynarek M, Pizer B, Dufour C, van Vuurden D, Garami M, Massimino M, Fangusaro J, Davidson T, Gil-da-Costa MJ, Sterba J, Benesch M, Gerber N, Juhnke BO, Kwiecien R, Pietsch T, Kool M, Clifford S, Ellison DW, Giangaspero F, Wesseling P, Gilles F, Gottardo N, Finlay JL, Rutkowski S, von Hoff K: Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data. Neuro-oncology 2017 Apr 1; 19: 576 [PMID: 28011926] MYN2017
  8. Friedrich C, Warmuth-Metz M, von Bueren AO, Nowak J, Bison B, von Hoff K, Pietsch T, Kortmann RD, Rutkowski S: Primitive neuroectodermal tumors of the brainstem in children treated according to the HIT trials: clinical findings of a rare disease. Journal of neurosurgery. Pediatrics 2015, 1 [PMID: 25555122] FRI2015
  9. Bode U, Zimmermann M, Moser O, Rutkowski S, Warmuth-Metz M, Pietsch T, Kortmann RD, Faldum A, Fleischhack G: Treatment of recurrent primitive neuroectodermal tumors (PNET) in children and adolescents with high-dose chemotherapy (HDC) and stem cell support: results of the HITREZ 97 multicentre trial. Journal of neuro-oncology 2014, 120: 635 [PMID: 25179451] BOD2014
  10. Gessi M, von Bueren AO, Treszl A, Mühlen AZ, Hartmann W, Warmuth-Metz M, Rutkowski S, Pietsch T: MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system. Neuro-oncology 2014, [PMID: 24470553] GES2014
  11. Gerber NU, von Hoff K, Resch A, Ottensmeier H, Kwiecien R, Faldum A, Matuschek C, Hornung D, Bremer M, Benesch M, Pietsch T, Warmuth-Metz M, Kuehl J, Rutkowski S, Kortmann RD: Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy. International journal of radiation oncology, biology, physics 2014, 89: 863 [PMID: 24969797] GER2014
  12. Friedrich C, von Bueren AO, von Hoff K, Gerber NU, Ottensmeier H, Deinlein F, Benesch M, Kwiecien R, Pietsch T, Warmuth-Metz M, Faldum A, Kuehl J, Kortmann RD, Rutkowski S: Treatment of young children with CNS-primitive neuroectodermal tumors/pineoblastomas in the prospective multicenter trial HIT 2000 using different chemotherapy regimens and radiotherapy. Neuro-oncology 2013, 15: 224 [PMID: 23223339] FRI2013
  13. Benesch M, Sperl D, von Bueren AO, Schmid I, von Hoff K, Warmuth-Metz M, Ferrari R, Lassay L, Kortmann RD, Pietsch T, Rutkowski S: Primary central nervous system primitive neuroectodermal tumors (CNS-PNETs) of the spinal cord in children: four cases from the German HIT database with a critical review of the literature. J Neurooncol 2010, Epub ahead of print [PMID: 21181235] BEN2010
  14. Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sörensen N, Kühl J: Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998, 16: 2478 [PMID: 9667267] SCH1998m
  15. Scheurlen W, Kühl J: Current diagnostic and therapeutic management of CNS metastasis in childhood primitive neuroectodermal tumors and ependymomas. Journal of neuro-oncology 1998, 38(2-3): 181 [PMID: 9696369] SCH1998l
  16. Scheurlen WG, Seranski P, Mincheva A, Kühl J, Sörensen N, Krauss J, Lichter P, Poustka A, Wilgenbus KK: High-resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11. 2. Genes, chromosomes & cancer 1997, 18: 50 [PMID: 8993980] SCH1997k

Low-grade glioma

Trial literature on low-grade glioma (LGG)

Pubmed

  1. Bergengruen PM, Hernaíz Driever P, Budach V, Zips D, Grün A: Second course of re-irradiation in pediatric diffuse intrinsic pontine glioma : A case study. Strahlentherapie und Onkologie 2023, [PMID: 36862153] BER2023
  2. Stock A, Hancken CV, Kandels D, Kortmann RD, Dietzsch S, Timmermann B, Pietsch T, Bison B, Schmidt R, Pham M, Gnekow AK, Warmuth-Metz M: Pseudoprogression Is Frequent After Front-Line Radiation Therapy in Pediatric Low-Grade Glioma: Results From the German Low-Grade Glioma Cohort. International journal of radiation oncology, biology, physics 2022, 112: 1190 [PMID: 34933039] STO2022
  3. Kilian A, Aigner A, Simon M, Salchow DJ, Potratz C, Thomale UW, Hernáiz Driever P, Tietze A: Tumor load rather than contrast enhancement is associated with the visual function of children and adolescents with optic pathway glioma - a retrospective Magnetic Resonance Imaging study. Journal of neuro-oncology 2022, 156: 589 [PMID: 34994964] KIL2022
  4. Thomale UW, Gnekow AK, Kandels D, Bison B, Hernáiz Driever P, Witt O, Pietsch T, Koch A, Capper D, Kortmann RD, Timmermann B, Harrabi S, Simon M, El Damaty A, Krauss J, Schuhmann MU, Aigner A: Long-term follow-up of surgical intervention pattern in pediatric low-grade gliomas: report from the German SIOP-LGG 2004 cohort. Journal of neurosurgery. Pediatrics 2022 Jul 22;: 1 [PMID: 35901673] THO2022
  5. Perwein T, Benesch M, Kandels D, Pietsch T, Schmidt R, Quehenberger F, Bison B, Warmuth-Metz M, Timmermann B, Krauss J, Thomale UW, Kortmann RD, Driever PH, Gnekow AK: High frequency of disease progression in pediatric spinal cord low-grade glioma (LGG): management strategies and results from the German LGG study group. Neuro-oncology 2021, 23: 1148 [PMID: 33346834] PER2021
  6. Fisher MJ, Jones DTW, Li Y, Guo X, Sonawane PS, Waanders AJ, Phillips JJ, Weiss WA, Resnick AC, Gosline S, Banerjee J, Guinney J, Gnekow A, Kandels D, Foreman NK, Korshunov A, Ryzhova M, Massimi L, Gururangan S, Kieran MW, Wang Z, Fouladi M, Sato M, Øra I, Holm S, Markham SJ, Beck P, Jäger N, Wittmann A, Sommerkamp AC, Sahm F, Pfister SM, Gutmann DH: Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1). Acta neuropathologica 2021, 141: 605 [PMID: 33585982] FIS2021
  7. Gnekow AK, Kandels D, Pietsch T, Bison B, Warmuth-Metz M, Thomale UW, Kortmann RD, Timmermann B, Driever PH, Witt O, Schmidt R, Spix C: Doubling Recruitment of Pediatric Low-grade Glioma within Two Decades does not change Outcome - Report from the German LGG Studies. Klinische Padiatrie 2021, 233: 107 [PMID: 33971689] GNE2021
  8. Fangusaro J, Witt O, Hernáiz Driever P, Bag AK, de Blank P, Kadom N, Kilburn L, Lober RM, Robison NJ, Fisher MJ, Packer RJ, Young Poussaint T, Papusha L, Avula S, Brandes AA, Bouffet E, Bowers D, Artemov A, Chintagumpala M, Zurakowski D, van den Bent M, Bison B, Yeom KW, Taal W, Warren KE: Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. The Lancet. Oncology 2020, 21:e305-e316 [PMID: 32502457] FAN2020
  9. Selt F, van Tilburg CM, Bison B, Sievers P, Harting I, Ecker J, Pajtler KW, Sahm F, Bahr A, Simon M, Jones DTW, Well L, Mautner VF, Capper D, Hernáiz Driever P, Gnekow A, Pfister SM, Witt O, Milde T: Response to trametinib treatment in progressive pediatric low-grade glioma patients. Journal of neuro-oncology 2020, 149: 499 [PMID: 33026636] SEL2020
  10. Gnekow AK, Kandels D, Tilburg CV, Azizi AA, Opocher E, Stokland T, Driever PH, Schouten-van Meeteren AYN, Thomale UW, Schuhmann MU, Czech T, Goodden JR, Warmuth-Metz M, Bison B, Avula S, Kortmann RD, Timmermann B, Pietsch T, Witt O: Correction: SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma. Klinische Padiatrie 2019, 231:e2 [PMID: 32079032] GNE2020
  11. Falkenstein F, Gessi M, Kandels D, Ng HK, Schmidt R, Warmuth-Metz M, Bison B, Krauss J, Kortmann RD, Timmermann B, Thomale UW, Albert MH, Pekrun A, Maaß E, Gnekow AK, Pietsch T: Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO-grade II-Report from the German/Swiss SIOP-LGG 2004 cohort. International journal of cancer 2020, Epup ahead of print [PMID: 32239677] FAL2020
  12. Gnekow AK, Kandels D, Tilburg CV, Azizi AA, Opocher E, Stokland T, Driever PH, Schouten-van Meeteren AYN, Thomale UW, Schuhmann MU, Czech T, Goodden JR, Warmuth-Metz M, Bison B, Avula S, Kortmann RD, Timmermann B, Pietsch T, Witt O: SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma. Klinische Padiatrie 2019, 231: 107 [PMID: 31108561] GNE2019
  13. Goebel AM, Gnekow AK, Kandels D, Witt O, Schmidt R, Hernáiz Driever P: Natural History of Pediatric Low-Grade Glioma Disease - First Multi-State Model Analysis. Journal of Cancer 2019, 10: 6314 [PMID: 31772664] GOE2019
  14. Jones DTW, Witt O, Pfister SM: BRAF V600E Status Alone Is Not Sufficient as a Prognostic Biomarker in Pediatric Low-Grade Glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2018, 36: 96 [PMID: 29140771] JON2018a
  15. Gnekow AK, Walker DA, Kandels D, Picton S, Giorgio Perilongo, Grill J, Stokland T, Sandstrom PE, Warmuth-Metz M, Pietsch T, Giangaspero F, Schmidt R, Faldum A, Kilmartin D, De Paoli A, De Salvo GL, Low Grade Glioma Consortium and the participating centers: Corrigendum to "A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma - A final report". European journal of cancer 2018, 90: 156 [PMID: 29248309] GNE2018a
  16. Kaufmann A, Gerber NU, Kandels D, Azizi AA, Schmidt R, Warmuth-Metz M, Pietsch T, Kortmann RD, Gnekow AK, Grotzer MA: Management of Primary Tectal Plate Low-Grade Glioma in Pediatric Patients: Results of the Multicenter Treatment Study SIOP-LGG 2004. Neuropediatrics 2018, 49: 314 [PMID: 29890518] KAU2018
  17. Jones DTW, Kieran MW, Bouffet E, Alexandrescu S, Bandopadhayay P, Bornhorst M, Ellison D, Fangusaro J, Fisher MJ, Foreman N, Fouladi M, Hargrave D, Hawkins C, Jabado N, Massimino M, Mueller S, Perilongo G, Schouten van Meeteren AYN, Tabori U, Warren K, Waanders AJ, Walker D, Weiss W, Witt O, Wright K, Zhu Y, Bowers DC, Pfister SM, Packer RJ: Pediatric low-grade gliomas: next biologically driven steps. Neuro-oncology 2018, 20: 160 [PMID: 29016845] JON2018
  18. Packer RJ, Pfister S, Bouffet E, Avery R, Bandopadhayay P, Bornhorst M, Bowers DC, Ellison D, Fangusaro J, Foreman N, Fouladi M, Gajjar A, Haas-Kogan D, Hawkins C, Ho CY, Hwang E, Jabado N, Kilburn LB, Lassaletta A, Ligon KL, Massimino M, Meeteren SV, Mueller S, Nicolaides T, Perilongo G, Tabori U, Vezina G, Warren K, Witt O, Zhu Y, Jones DT, Kieran M: Pediatric low-grade gliomas: implications of the biologic era. Neuro-oncology 2017, 19: 750 [PMID: 27683733] PAC2017
  19. Gnekow AK, Walker DA, Kandels D, Picton S, Giorgio Perilongo, Grill J, Stokland T, Sandstrom PE, Warmuth-Metz M, Pietsch T, Giangaspero F, Schmidt R, Faldum A, Kilmartin D, De Paoli A, De Salvo GL, of the Low Grade Glioma Consortium and the participating centers: A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma - A final report. European journal of cancer (Oxford, England : 1990) 2017, 81: 206 [PMID: 28649001] GNE2017
  20. Mirow C, Pietsch T, Berkefeld S, Kwiecien R, Warmuth-Metz M, Falkenstein F, Diehl B, von Hornstein S, Gnekow AK: Children <1 year show an inferior outcome when treated according to the traditional LGG treatment strategy: a report from the German multicenter trial HIT-LGG 1996 for children with low grade glioma (LGG). Pediatric blood & cancer 2014, 61: 457 [PMID: 24039013] MIR2014
  21. Müller K, Gnekow A, Falkenstein F, Scheiderbauer J, Zwiener I, Pietsch T, Warmuth-Metz M, Voges J, Nikkhah G, Flentje M, Combs SE, Vordermark D, Kocher M, Kortmann RD: Radiotherapy in pediatric pilocytic astrocytomas : A subgroup analysis within the prospective multicenter study HIT-LGG 1996 by the German Society of Pediatric Oncology and Hematology (GPOH). Strahlentherapie und Onkologie 2013, 189: 647 [PMID: 23831852] MUE2013
  22. Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM: Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer cell 2012, 22: 425 [PMID: 23079654] STU2012
  23. Gnekow AK, Falkenstein F, von Hornstein S, Zwiener I, Berkefeld S, Bison B, Warmuth-Metz M, Driever PH, Soerensen N, Kortmann RD, Pietsch T, Faldum A: Long-term follow-up of the multicenter, multidisciplinary treatment study HIT-LGG-1996 for low-grade glioma in children and adolescents of the German Speaking Society of Pediatric Oncology and Hematology. Neuro-oncology 2012, 14: 1265 [PMID: 22942186] GNE2012
  24. von Hornstein S, Kortmann RD, Pietsch T, Emser A, Warmuth-Metz M, Soerensen N, Straeter R, Graf N, Thieme B, Gnekow AK: Impact of chemotherapy on disseminated low-grade glioma in children and adolescents: report from the HIT-LGG 1996 trial. Pediatric blood & cancer 2011 Jul 1; 56: 1046 [PMID: 21319282] HOR2011
  25. Hupp M, Falkenstein F, Bison B, Mirow C, Krauß J, Gnekow A, Solymosi L, Warmuth-Metz M: Infarction following chiasmatic low grade glioma resection. Child's nervous system 2011,Epub ahead of print [PMID: 21987345] HUP2011
  26. Korinthenberg R, Neuburger D, Nikkhah G, Teske C, Schnabel K, Calaminus G: Assessing Quality of Life in Long-Term Survivors after 125I Brachytherapy for Low-Grade Glioma in Childhood. Neuropediatrics 2011, 42: 110 [PMID: 21739406] KOR2011
  27. Rokes CA, Remke M, Guha-Thakurta N, Witt O, Korshunov A, Pfister S, Wolff JE: Sorafenib plus valproic acid for infant spinal glioblastoma. J Pediatr Hematol Oncol 2010, 32: 511 [DOI: 20463608] ROK2010
  28. Hernáiz Driever P, von Hornstein S, Pietsch T, Kortmann R, Warmuth-Metz M, Emser A, Gnekow AK: Natural history and management of low-grade glioma in NF-1 children. J Neurooncol 2010, [PMID: 20352473] HER2010
  29. Scheiderbauer J, Gnekow AK, Emser A, Hildebrandt G, Bamberg M, Kortmann RD: Multizentrische prospektive kooperative Studie SIOP/GPOH „Low grade glioma„ im Kindesalter von 1996: Ergebnisse nach Strahlentherapie (Deutschland). Strahlenther Onkol 2005, 181 (Sondernr 1): 39 SCH2005g
  30. Gnekow AK, Scheiderbauer J, Pietsch T, Soerensen N, Faldum A, Emser A, von Hornstein S, Warmuth-Metz M, Kuehl J: HIT-LGG 1996-Success of a countrywide, comprehensive treatment strategy for children and adolescents with low grade glioma of all histologies and locations. Pedriatric Blood and Cancer 2005, 45: 465 GNE2005a
  31. Gnekow AK, Kortmann RD, Pietsch T, Emser A: Low grade chiasmatic-hypothalamic glioma-carboplatin and vincristin chemotherapy effectively defers radiotherapy within a comprehensive treatment strategy -- report from the multicenter treatment study for children and adolescents with a low grade glioma -- HIT-LGG 1996 -- of the Society of Pediatric Oncology and Hematology (GPOH). Klinische Padiatrie 2004, 216: 331 [PMID: 15565548] GNE2004a
  32. Peters O, Gnekow AK, Rating D, Wolff JE: Impact of location on outcome in children with low-grade oligodendroglioma. Pediatric blood & cancer 2004, 43: 250 [PMID: 15266409] PET2004
  33. Peters U, Preisler-Adams S, Lanvers-Kaminsky C, Jürgens H, Lamprecht-Dinnesen A: Sequence variations of mitochondrial DNA and individual sensitivity to the ototoxic effect of cisplatin. Anticancer Res 2003, 23: 1249 PET2003a

High-grade glioma / Glioblastoma

Trial literature on high-grade gliomas (HGG) / Glioblastoma multiforme (GBM)

Pubmed

  1. Fleischhack G, Massimino M, Warmuth-Metz M, Khuhlaeva E, Janssen G, Graf N, Rutkowski S, Beilken A, Schmid I, Biassoni V, Gorelishev SK, Kramm C, Reinhard H, Schlegel PG, Kortmann RD, Reuter D, Bach F, Iznaga-Escobar NE, Bode U: Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study. Journal of neuro-oncology 2019, 143: 107 [PMID: 30830679] FLE2019
  2. Pfaff E, El Damaty A, Balasubramanian GP, Blattner-Johnson M, Worst BC, Stark S, Witt H, Pajtler KW, van Tilburg CM, Witt R, Milde T, Jakobs M, Fiesel P, Frühwald MC, Hernáiz Driever P, Thomale UW, Schuhmann MU, Metzler M, Bochennek K, Simon T, Dürken M, Karremann M, Knirsch S, Ebinger M, von Bueren AO, Pietsch T, Herold-Mende C, Reuss DE, Kiening K, Lichter P, Eggert A, Kramm CM, Pfister SM, Jones DTW, Bächli H, Witt O: Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience. European journal of cancer 2019, 114: 27 [PMID: 31022591] PFA2019
  3. Castel D, Philippe C, Kergrohen T, Sill M, Merlevede J, Barret E, Puget S, Sainte-Rose C, Kramm CM, Jones C, Varlet P, Pfister SM, Grill J, Jones DTW, Debily MA: Transcriptomic and epigenetic profiling of 'diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location. Acta neuropathologica communications 2018 Nov 5; 6: 117 [PMID: 30396367] CAS2018a
  4. Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M: Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries. Journal of clinical oncology 2018 Jul 1; 36: 1963 [PMID: 29746225] HOF2018
  5. Seidel C, von Bueren AO, Bojko S, Hoffmann M, Pietsch T, Gielen GH, Warmuth-Metz M, Bison B, Kortmann RD, Kramm CM: Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients. Strahlentherapie und Onkologie 2018, 194: 215 [PMID: 29022050] SEI2018
  6. Karremann M, Gielen GH, Hoffmann M, Wiese M, Colditz N, Warmuth-Metz M, Bison B, Claviez A, van Vuurden DG, von Bueren AO, Gessi M, Kühnle I, Hans VH, Benesch M, Sturm D, Kortmann RD, Waha A, Pietsch T, Kramm CM: Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location. Neuro-oncology 2018 Jan 10; 20: 123 [PMID: 29016894] KAR2018
  7. Wiese M, Walther N, Diederichs C, Schill F, Monecke S, Salinas G, Sturm D, Pfister SM, Dressel R, Johnsen SA, Kramm CM: The ß-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner. Oncotarget 2017 Apr 18; 8: 27300 [PMID: 28460484] WIE2017
  8. Karremann M, Krämer N, Hoffmann M, Wiese M, Beilken A, Corbacioglu S, Dilloo D, Driever PH, Scheurlen W, Kulozik A, Gielen GH, von Bueren AO, Dürken M, Kramm CM: Haematological malignancies following temozolomide treatment for paediatric high-grade glioma. European journal of cancer (Oxford, England : 1990) 2017, 81: 1 [PMID: 28586748] KAR2017
  9. El-Ayadi M, Ansari M, Sturm D, Gielen GH, Warmuth-Metz M, Kramm CM, von Bueren AO: High-grade glioma in very young children: a rare and particular patient population. Oncotarget 2017 Sep 8; 8: 64564 [PMID: 28969094] ELA2017
  10. Müller K, Scheithauer H, Pietschmann S, Hoffmann M, Rössler J, Graf N, Baumert BG, Christiansen H, Kortmann RD, Kramm CM, von Bueren AO: Reirradiation as part of a salvage treatment approach for progressive non-pontine pediatric high-grade gliomas: preliminary experiences from the German HIT-HGG study group. Radiation oncology 2014, 9: 177 [PMID: 25112658] MUE2014b
  11. Müller K, Schlamann A, Guckenberger M, Warmuth-Metz M, Glück A, Pietschmann S, Wawer A, Kortmann RD, Kramm C, von Bueren AO: Craniospinal irradiation with concurrent temozolomide for primary metastatic pediatric high-grade or diffuse intrinsic pontine gliomas. A first report from the GPOH-HIT-HGG Study Group. Strahlentherapie und Onkologie 2014, 190: 377 [PMID: 24638239] MUE2014
  12. Müller K, Schlamann A, Seidel C, Warmuth-Metz M, Christiansen H, Vordermark D, Kortmann RD, Kramm CM, von Bueren AO: Craniospinal irradiation with concurrent temozolomide and nimotuzumab in a child with primary metastatic diffuse intrinsic pontine glioma : A compassionate use treatment. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 2013, 189: 693 [PMID: 23754473] MUE2013a
  13. Leonard A, Wolff JE: Etoposide Improves Survival in High-grade Glioma: A Meta-Analysis. Anticancer research 2013, 33: 3307 [PMID: 23898097] LEO2013
  14. Karremann M, Rausche U, Roth D, Kühn A, Pietsch T, Gielen GH, Warmuth-Metz M, Kortmann RD, Straeter R, Gnekow A, Wolff JE, Kramm CM: Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma. British journal of cancer 2013, epub ahead of print [PMID: 23868007] KAR2013
  15. Gielen GH, Gessi M, Hammes J, Kramm CM, Waha A, Pietsch T: H3F3A K27M mutation in pediatric CNS tumors: a marker for diffuse high-grade astrocytomas. American journal of clinical pathology 2013, 139: 345 [PMID: 23429371] GIE2013
  16. Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM: Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer cell 2012, 22: 425 [PMID: 23079654] STU2012
  17. Wolff JE, Rytting ME, Vats TS, Zage PE, Ater JL, Woo S, Kuttesch J, Ketonen L, Mahajan A: Treatment of recurrent diffuse intrinsic pontine glioma: the MD Anderson Cancer Center experience. Journal of neuro-oncology 2011,Epub ahead of print [PMID: 21858608] WOL2011a
  18. Wolff B, Ng A, Roth D, Parthey K, Warmuth-Metz M, Eyrich M, Kordes U, Kortmann R, Pietsch T, Kramm C, Wolff JE: Pediatric high grade glioma of the spinal cord: results of the HIT-GBM database. Journal of neuro-oncology 2011,Epub ahead of print [PMID: 21964697] WOL2011
  19. MacDonald TJ, Aguilera D, Kramm CM: Treatment of high-grade glioma in children and adolescents. Neuro Oncol 2011, [Epub ahead of print] [PMID: 21784756] MAC2011
  20. Kramm CM, Butenhoff S, Rausche U, Warmuth-Metz M, Kortmann RD, Pietsch T, Gnekow A, Jorch N, Janssen G, Berthold F, Wolff JE: Thalamic high-grade gliomas in children: a distinct clinical subset? Neuro Oncol 2011, 13: 680 [PMID: 21636712] KRA2011
  21. Wolff JE, Mohiuddin K, Jorch N, Graf N, Wagner S, Vats T, Gnekow A: Measuring performance status in pediatric patients with brain tumors--experience of the HIT-GBM-C protocol. Pediatr Blood Cancer 2010, 55: 520 [PMID: 20658624] WOL2010a
  22. Rokes CA, Remke M, Guha-Thakurta N, Witt O, Korshunov A, Pfister S, Wolff JE: Sorafenib plus valproic acid for infant spinal glioblastoma. J Pediatr Hematol Oncol 2010, 32: 511 [DOI: 20463608] ROK2010
  23. Wolff JE, Driever PH, Erdlenbruch B, Kortmann RD, Rutkowski S, Pietsch T, Parker C, Metz MW, Gnekow A, Kramm CM: Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol. Cancer 2010, 116: 705 [PMID: 19957326] WOL2010
  24. Karremann M, Pietsch T, Janssen G, Kramm CM, Wolff JE: Anaplastic ganglioglioma in children. J Neurooncol 2009, 92: 157 [PMID: 19043777] KAR2009b
  25. Karremann M, Butenhoff S, Rausche U, Pietsch T, Wolff JE, Kramm CM: Pediatric giant cell glioblastoma: New insights into a rare tumor entity. Neuro-oncology 2009, 11: 323 [PMID: 19050301] KAR2009
  26. Wolff JE, Classen CF, Wagner S, Kortmann RD, Palla SL, Pietsch T, Kühl J, Gnekow A, Kramm CM: Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database. J Neurooncol 2008, 87: 155 [PMID: 18209954] WOL2008b
  27. Wolff JE, Berrak S, Koontz Webb SE, Zhang M: Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients. J Neurooncol 2008, 88: 57 [PMID: 18253699] WOL2008a
  28. Masoudi A, Elopre M, Amini E, Nagel ME, Ater JL, Gopalakrishnan V, Wolff JE: Influence of valproic acid on outcome of high-grade gliomas in children. Anticancer Res 2008, 28: 2437 [PMID: 18751431] MAS2008
  29. Wolff JE, Kramm C, Kortmann RD, Pietsch T, Rutkowski S, Jorch N, Gnekow A, Driever PH: Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma. J Neurooncol 2008, 90: 309 [PMID: 18679579] WOL2008
  30. Wagner S, Benesch M, Berthold F, Gnekow AK, Rutkowski S, Sträter R, Warmuth-Metz M, Kortmann RD, Pietsch T, Wolff JE: Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas. Br J Cancer 95: 991 [PMID: 17047647] WAG2006
  31. Kramm CM, Wagner S, Van Gool S, Schmid H, Strater R, Gnekow A, Rutkowski S, Wolff JE: Improved survival after gross total resection of malignant gliomas in pediatric patients from the HIT-GBM studies. Anticancer Res 2006, 26: 3773 [PMID: 17094400] KRA2006

Choroid plexus tumours

Trial literature on choroid plexus tumours (CPT)

Pubmed

  1. Wolff JE, Van Gool SW, Kutluk T, Diez B, Kebudi R, Timmermann B, Garami M, Sterba J, Fuller GN, Bison B, Kordes UR: Final results of the Choroid Plexus Tumor study CPT-SIOP-2000. Journal of neuro-oncology 2022, 156: 599 [PMID: 34997889] WOL2022
  2. Thomas C, Oehl-Huber K, Bens S, Soschinski P, Koch A, Nemes K, Oyen F, Kordes U, Kool M, Frühwald MC, Hasselblatt M, Siebert R: Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor. Genes, chromosomes & cancer 2021, 60: 586 [PMID: 33896072] THO2021
  3. Thomas C, Soschinski P, Zwaig M, Oikonomopoulos S, Okonechnikov K, Pajtler KW, Sill M, Schweizer L, Koch A, Neumann J, Schüller U, Sahm F, Rauschenbach L, Keyvani K, Proescholdt M, Riemenschneider MJ, Segewiß J, Ruckert C, Grauer O, Monoranu CM, Lamszus K, Patrizi A, Kordes U, Siebert R, Kool M, Ragoussis J, Foulkes WD, Paulus W, Rivera B, Hasselblatt M: The genetic landscape of choroid plexus tumors in children and adults. Neuro-oncology 2021, 23: 650 [PMID: 33249490] THO2021
  4. Thomas C, Metrock K, Kordes U, Hasselblatt M, Dhall G: Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors. Journal of neuro-oncology 2020, Epup ahead of print [PMID: 32342334] THO2020a
  5. Ripperger T, Bielack SS, Borkhardt A, Brecht IB, Burkhardt B, Calaminus G, Debatin KM, Deubzer H, Dirksen U, Eckert C, Eggert A, Erlacher M, Fleischhack G, Frühwald MC, Gnekow A, Goehring G, Graf N, Hanenberg H, Hauer J, Hero B, Hettmer S, von Hoff K, Horstmann M, Hoyer J, Illig T, Kaatsch P, Kappler R, Kerl K, Klingebiel T, Kontny U, Kordes U, Körholz D, Koscielniak E, Kramm CM, Kuhlen M, Kulozik AE, Lamottke B, Leuschner I, Lohmann DR, Meinhardt A, Metzler M, Meyer LH, Moser O, Nathrath M, Niemeyer CM, Nustede R, Pajtler KW, Paret C, Rasche M, Reinhardt D, Rieß O, Russo A, Rutkowski S, Schlegelberger B, Schneider D, Schneppenheim R, Schrappe M, Schroeder C, von Schweinitz D, Simon T, Sparber-Sauer M, Spix C, Stanulla M, Steinemann D, Strahm B, Temming P, Thomay K, von Bueren AO, Vorwerk P, Witt O, Wlodarski M, Wössmann W, Zenker M, Zimmermann S, Pfister SM, Kratz CP: Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology. American journal of medical genetics. Part A 2017, 173: 1017 [PMID: 28168833] RIP2017
  6. Thomas C, Sill M, Ruland V, Witten A, Hartung S, Kordes U, Jeibmann A, Beschorner R, Keyvani K, Bergmann M, Mittelbronn M, Pietsch T, Felsberg J, Monoranu CM, Varlet P, Hauser P, Olar A, Grundy RG, Wolff JE, Korshunov A, Jones DT, Bewerunge-Hudler M, Hovestadt V, von Deimling A, Pfister SM, Paulus W, Capper D, Hasselblatt M: Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups. Neuro-oncology 2016, 18: 790 [PMID: 26826203] THO2016
  7. Japp AS, Gessi M, Messing-Jünger M, Denkhaus D, Zur Mühlen A, Wolff JE, Hartung S, Kordes U, Klein-Hitpass L, Pietsch T: High-resolution genomic analysis does not qualify atypical plexus papilloma as a separate entity among choroid plexus tumors. Journal of neuropathology and experimental neurology 2015, 74: 110 [PMID: 25575132] JAP2015
  8. Thomas C, Ruland V, Kordes U, Hartung S, Capper D, Pietsch T, Gerß J, Wolff JE, Paulus W, Hasselblatt M: Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children. Acta neuropathologica 2015, 129: 925 [PMID: 25935663] THO2015
  9. Bahar M, Kordes U, Tekautz T, Wolff J: Radiation therapy for choroid plexus carcinoma patients with Li-Fraumeni syndrome: advantageous or detrimental? Anticancer research 2015, 35: 3013 [PMID: 25964589] BAH2015
  10. Ruland V, Hartung S, Kordes U, Wolff JE, Paulus W, Hasselblatt M: Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis. Genes, chromosomes & cancer 2014, 53: 373 [PMID: 24478045] RUL2014
  11. Krzyzankova M, Mertsch S, Koos B, Jeibmann A, Kruse A, Kordes U, Frühwald MC, Wolff JE, Paulus W, Hasselblatt M: Loss of TP53 expression in immortalized choroid plexus epithelial cells results in increased resistance to anticancer agents. Journal of neuro-oncology 2012, 109: 449 [PMID: 22763759] KRZ2012
  12. Berrak SG, Liu DD, Wrede B, Wolff JE: Which therapy works better in choroid plexus carcinomas? J Neurooncol 2011, 103: 155 [PMID: 20976614] BER2011
  13. Mazloom A, Wolff JE, Paulino AC: The impact of radiotherapy fields in the treatment of patients with choroid plexus carcinoma. Int J Radiat Oncol Biol Phys 2010, 78: 79 [PMID: 20004534] MAZ2010
  14. Subbiah V, Ketonen L, Bruner JM, Nunez R, Weinberg J, Wolff JE: 99mTc-sestamibi scan differentiates tumor from other contrast enhancing tissue in choroid plexus tumors. J Clin Onco 2010, 32: 160 [PMID: 20168252] SUB2010
  15. Berrak SG, Liu DD, Wrede B, Wolff JE: Which therapy works better in choroid plexus carcinomas? J Neurooncol 2010, Epub ahead of print [PMID: 20976614] BER2010
  16. Hasselblatt M, Mühlisch J, Wrede B, Kallinger B, Jeibmann A, Peters O, Kutluk T, Wolff JE, Paulus W, Frühwald MC: Aberrant MGMT (O6-methylguanine-DNA methyltransferase) promoter methylation in choroid plexus tumors. J Neurooncol 2009, 91: 151 [PMID: 18795231] HAS2009
  17. Prasad P, Vasquez H, Das CM, Gopalakrishnan V, Wolff JE: Histone acetylation resulting in resistance to methotrexate in choroid plexus cells. J Neurooncol 2009, 91: 279 [PMID: 18853233] PRA2009
  18. Wrede B, Hasselblatt M, Peters O, Thall PF, Kutluk T, Moghrabi A, Mahajan A, Rutkowski S, Diez B, Wang X, Pietsch T, Kortmann RD, Paulus W, Jeibmann A, Wolff JE: Atypical choroid plexus papilloma: clinical experience in the CPT-SIOP-2000 study. J Neurooncol 2009, 95: 383 [PMID: 19543851] WRE2009
  19. Wrede B, Liu P, Wolff JE: Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid plexus tumors. J Neurooncol 2007, 85: 345 [PMID: 17576522] WRE2007

Rhabdoid tumours of the CNS (AT/RT)

Trial literature on cerebral rhabdoid tumours (AT/RT)

Pubmed

  1. Johann PD, Altendorf L, Efremova EM, Holsten T, Steinbügl M, Nemes K, Eckhardt A, Kresbach C, Bockmayr M, Koch A, Haberler C, Antonelli M, DeSisto J, Schuhmann MU, Hauser P, Siebert R, Bens S, Kool M, Green AL, Hasselblatt M, Frühwald MC, Schüller U: Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics. Acta neuropathologica 2023, 146: 527 [PMID: 37450044] JOH2023
  2. Nemes K, Johann PD, Steinbügl M, Gruhle M, Bens S, Kachanov D, Teleshova M, Hauser P, Simon T, Tippelt S, Eberl W, Chada M, Lopez VS, Grigull L, Hernáiz-Driever P, Eyrich M, Pears J, Milde T, Reinhard H, Leipold A, van de Wetering M, Gil-da-Costa MJ, Ebetsberger-Dachs G, Kerl K, Lemmer A, Boztug H, Furtwängler R, Kordes U, Vokuhl C, Hasselblatt M, Bison B, Kröncke T, Melchior P, Timmermann B, Gerss J, Siebert R, Frühwald MC: Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population. Cancers 2022, 14 [PMID: 35565313] NEM2022
  3. Nemes K, Johann PD, Steinbügl M, Gruhle M, Bens S, Kachanov D, Teleshova M, Hauser P, Simon T, Tippelt S, Eberl W, Chada M, Lopez VS, Grigull L, Hernáiz-Driever P, Eyrich M, Pears J, Milde T, Reinhard H, Leipold A, van de Wetering M, Gil-da-Costa MJ, Ebetsberger-Dachs G, Kerl K, Lemmer A, Boztug H, Furtwängler R, Kordes U, Vokuhl C, Hasselblatt M, Bison B, Kröncke T, Melchior P, Timmermann B, Gerss J, Siebert R, Frühwald MC: Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population. Cancers 2022, 14 [PMID: 35565313] NEM2022
  4. Federico A, Thomas C, Miskiewicz K, Woltering N, Zin F, Nemes K, Bison B, Johann PD, Hawes D, Bens S, Kordes U, Albrecht S, Dohmen H, Hauser P, Keyvani K, van Landeghem FKH, Lund EL, Scheie D, Mawrin C, Monoranu CM, Parm Ulhøi B, Pietsch T, Reinhard H, Riemenschneider MJ, Sehested A, Sumerauer D, Siebert R, Paulus W, Frühwald MC, Kool M, Hasselblatt M: ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance. Acta neuropathologica 2022, 143: 697 [PMID: 35501487] FED2022
  5. Blümel L, Qin N, Berlandi J, Paisana E, Cascão R, Custódia C, Pauck D, Picard D, Langini M, Stühler K, Meyer FD, Göbbels S, Malzkorn B, Liebau MC, Barata JT, Jeibmann A, Kerl K, Erkek S, Kool M, Pfister SM, Johann PD, Frühwald MC, Borkhardt A, Reifenberger G, Faria CC, Fischer U, Hasselblatt M, Bartl J, Remke M: Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors. Cell death & disease 2022, 13: 806 [PMID: 36127323] BLU2022
  6. Pathak R, Zin F, Thomas C, Bens S, Gayden T, Karamchandani J, Dudley RW, Nemes K, Johann PD, Oyen F, Kordes U, Jabado N, Siebert R, Paulus W, Kool M, Frühwald MC, Albrecht S, Kalpana GV, Hasselblatt M: Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors. Acta neuropathologica 2021, 142: 361 [PMID: 34003336] PAT2021
  7. Hasselblatt M, Thomas C, Nemes K, Monoranu CM, Riemenschneider MJ, Koch A, Sumerauer D, Hauser P, Paulus W, Johann PD, Kool M, Frühwald MC: Tyrosinase immunohistochemistry can be employed for the diagnosis of atypical teratoid/rhabdoid tumours of the tyrosinase subgroup (ATRT-TYR). Neuropathology and applied neurobiology 2020, 46: 186 [PMID: 31077608] HAS2020
  8. Melcher V, Graf M, Interlandi M, Moreno N, de Faria FW, Kim SN, Kastrati D, Korbanka S, Alfert A, Gerß J, Meyer Zu Hörste G, Hartmann W, Frühwald MC, Dugas M, Schüller U, Hasselblatt M, Albert TK, Kerl K: Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance. Acta neuropathologica 2020, 139: 913 [PMID: 31848709] MEL2020
  9. Thomas C, Wefers A, Bens S, Nemes K, Agaimy A, Oyen F, Vogelgesang S, Rodriguez FJ, Brett FM, McLendon R, Bodi I, Burel-Vandenbos F, Keyvani K, Tippelt S, Poulsen FR, Lipp ES, Giannini C, Reifenberger G, Kuchelmeister K, Pietsch T, Kordes U, Siebert R, Frühwald MC, Johann PD, Sill M, Kool M, von Deimling A, Paulus W, Hasselblatt M: Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults. Acta neuropathologica 2020, 139: 277 [PMID: 31732806] THO2020
  10. Thomas C, Knerlich-Lukoschus F, Reinhard H, Johann PD, Sturm D, Sahm F, Bens S, Vogt J, Nemes K, Oyen F, Kordes U, Siebert R, Schneppenheim R, Messing-Jünger M, Pietsch T, von Deimling A, Paulus W, Pfister SM, Kool M, Frühwald MC, Hasselblatt M: Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1. Acta neuropathologica 2019, 137: 847 [PMID: 30945057] THO2019a
  11. Tegeder I, Thiel K, Erkek S, Johann PD, Berlandi J, Thatikonda V, Frühwald MC, Kool M, Jeibmann A, Hasselblatt M: Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Journal of neuro-oncology 2019, 141: 43 [PMID: 30446899] TEG2019
  12. Nemes K, Clément N, Kachanov D, Bens S, Hasselblatt M, Timmermann B, Schneppenheim R, Gerss J, Siebert R, Furtwängler R, Bourdeaut F, Frühwald MC, EU-RHAB consortium: The extraordinary challenge of treating patients with congenital rhabdoid tumors-a collaborative European effort. Pediatric blood & cancer 2018, 65:e26999 [PMID: 29418059] NEM2018a
  13. Nowak J, Nemes K, Hohm A, Vandergrift LA, Hasselblatt M, Johann PD, Kool M, Frühwald MC, Warmuth-Metz M: Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor. Neuro-oncology 2018 Nov 12; 20: 1672 [PMID: 30010851] NOW2018
  14. Kehrer-Sawatzki H, Kordes U, Seiffert S, Summerer A, Hagel C, Schüller U, Farschtschi S, Schneppenheim R, Bendszus M, Godel T, Mautner VF: Co-occurrence of schwannomatosis and rhabdoid tumor predisposition syndrome 1. Molecular genetics & genomic medicine 2018, [PMID: 29779243] KEH2018
  15. Nemes K, Frühwald MC: Emerging therapeutic targets for the treatment of malignant rhabdoid tumors. Expert opinion on therapeutic targets 2018, 22: 365 [PMID: 29528755] NEM2018
  16. Hasselblatt M, Johann PD, Kool M, Frühwald MC: Reduced histone H3 K27 trimethylation is encountered in about 50% of atypical teratoid/rhabdoid tumors (AT/RT) but is not associated with molecular subgroup status and outcome. Acta neuropathologica 2017, 134: 817 [PMID: 28815304] HAS2017
  17. Nemes K, Bens S, Bourdeaut F, Hasselblatt M, Kool M, Johann P, Kordes U, Schneppenheim R, Siebert R, Frühwald MC, In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A (eds): Rhabdoid Tumor Predisposition Syndrome. GeneReviews 2017 [PMID: 29215836] NEM2017
  18. Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann RD, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel PG, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, Frühwald MC: Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007. Cancer medicine 2016, [PMID: 27228363] BAR2016a
  19. Frühwald MC, Biegel JA, Bourdeaut F, Roberts CW, Chi SN: Atypical teratoid/rhabdoid tumors-current concepts, advances in biology, and potential future therapies. Neuro-oncology 2016, 18: 764 [PMID: 26755072] FRU2016
  20. Kerl K, Oyen F, Giannikopoulou D, Rössig C, Rellensmann G, Sandkötter J, Brentrup A, Selzer G, Schneppenheim R, Frühwald MC: Rapid Diagnosis of an AT/RT by the Detection of a Heterozygous SMARCB1 Germ Line Deletion in an Infant. Pediatric blood & cancer 2016, 63: 1451 [PMID: 27092963] KER2016
  21. Bento C, Percy MJ, Gardie B, Maia TM, van Wijk R, Perrotta S, Della Ragione F, Almeida H, Rossi C, Girodon F, Aström M, Neumann D, Schnittger S, Landin B, Minkov M, Randi ML, Richard S, Casadevall N, Vainchenker W, Rives S, Hermouet S, Ribeiro ML, McMullin MF, Cario H, ECE-Consortium, Chauveau A, Gimenez-Roqueplo AP, Bressac-de-Paillerets B, Altindirek D, Lorenzo F, Lambert F, Dan H, Gad-Lapiteau S, Catarina Oliveira A, Rossi C, Fraga C, Taradin G, Martin-Nuñez G, Vitória H, Diaz Aguado H, Palmblad J, Vidán J, Relvas L, Ribeiro ML, Luigi Larocca M, Luigia Randi M, Pedro Silveira M, Percy M, Gross M, Marques da Costa R, Beshara S, Ben-Ami T, Ugo V, ECE-Consortium: Genetic basis of congenital erythrocytosis: mutation update and online databases. Human mutation 2014, 35: 15 [PMID: 24115288] BEN2014
  22. Hasenclever D, Kurch L, Mauz-Körholz C, Elsner A, Georgi T, Wallace H, Landman-Parker J, Moryl-Bujakowska A, Cepelová M, Karlén J, Álvarez Fernández-Teijeiro A, Attarbaschi A, Fosså A, Pears J, Hraskova A, Bergsträsser E, Beishuizen A, Uyttebroeck A, Schomerus E, Sabri O, Körholz D, Kluge R: qPET - a quantitative extension of the Deauville scale to assess response in interim FDG-PET scans in lymphoma. European journal of nuclear medicine and molecular imaging 2014, 41: 1301 [PMID: 24604592] HAS2014
  23. Warmuth-Metz M, Bison B, Gerber NU, Pietsch T, Hasselblatt M, Frühwald MC: Bone Involvement in Atypical Teratoid/Rhabdoid Tumors of the CNS. AJNR. American journal of neuroradiology 2013, Epub ahead of print [PMID: 23681355] WAR2013
  24. von Hoff K, Hinkes B, Dannenmann-Stern E, von Bueren AO, Warmuth-Metz M, Soerensen N, Emser A, Zwiener I, Schlegel PG, Kuehl J, Frühwald MC, Kortmann RD, Pietsch T, Rutkowski S: Frequency, risk-factors and survival of children with atypical teratoid rhabdoid tumors (AT/RT) of the CNS diagnosed between 1988 and 2004, and registered to the German HIT database. Pediatric blood & cancer 2011, 1; 57: 978 [PMID: 21796761] HOF2011a
  25. Hasle H, Niemeyer CM: Advances in the prognostication and management of advanced MDS in children. Br J Haematol 2011, 154: 185 [PMID: 21554264] HAS2011
  26. Hof J, Krentz S, van Schewick C, Körner G, Shalapour S, Rhein P, Karawajew L, Ludwig WD, Seeger K, Henze G, von Stackelberg A, Hagemeier C, Eckert C, Kirschner-Schwabe R: Mutations and Deletions of the TP53 Gene Predict Nonresponse to Treatment and Poor Outcome in First Relapse of Childhood Acute Lymphoblastic Leukemia. J Clin Oncol 2011, [Epub ahead of print] [PMID: 21747090] HOF2011
  27. Mühlisch J, Schwering A, Grotzer M, Vince GH, Roggendorf W, Hagemann C, Sörensen N, Rickert CH, Osada N, Jürgens H, Früwald MC: Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood. Oncogene 2006, 25: 1111 [PMID: 16186793] MUE2006c

Craniopharyngeoma

Trial literature on craniopharyngeoma

Pubmed

  1. Beckhaus J, Friedrich C, Boekhoff S, Calaminus G, Bison B, Eveslage M, Timmermann B, Flitsch J, Müller HL: Outcome after pediatric craniopharyngioma: the role of age at diagnosis and hypothalamic damage. European journal of endocrinology 2023, 188 [PMID: 36857103] BEC2023b
  2. Beckhaus J, Friedrich C, Müller HL: Childhood-onset craniopharyngioma - a life-long family burden? The Journal of clinical endocrinology and metabolism 2023, [PMID: 37847153] BEC2023a
  3. Böhm S, Wustrau K, Pachlopnik Schmid J, Prader S, Ahlman M, Yacobovich J, Beier R, Speckmann C, Behnisch W, Ifversen M, Jordan MB, Marsh RA, Naumann-Bartsch N, Mauz-Koerholz C, Honig M, Schulz AS, Malinowska I, Hines MR, Nichols KE, Gil-Herrera J, Talano JA, Crooks B, Formankova R, Jorch N, Bakhtiar S, Kühnle I, Streiter M, Nathrath M, Russo A, Duerken M, Lang P, Lindemans CA, Henter JI, Lehmberg K, Ehl S: Survival in primary hemophagocytic lymphohistiocytosis 2016-2021: etoposide is better than its reputation. Blood 2023 Nov 22; [PMID: 37992218] BOE2023
  4. Boekhoff S, Eveslage M, Beckhaus J, Friedrich C, Müller HL: [Legal Degree of Disability in Childhood-Craniopharyngioma Survivors During Long-Term Follow-Up]. Klinische Padiatrie 2023, 235: 151 [PMID: 36379455] BOE2023
  5. Apps JR, Muller HL, Hankinson TC, Yock TI, Martinez-Barbera JP: Contemporary Biological Insights and Clinical Management of Craniopharyngioma. Endocrine reviews 2023, 44: 518 [PMID: 36574377] APP2023
  6. Beckhaus J, Boekhoff S, Scheinemann K, Schilling FH, Fleischhack G, Binder G, Bison B, Pietsch T, Friedrich C, Müller HL: Perinatally diagnosed congenital craniopharyngiomas in the KRANIOPHARYNGEOM trials. Endocrine connections 2023,Oct [PMID: 37878777] BEC2023
  7. Müller HL: Bariatric Interventions in Craniopharyngioma Patients-Best Choice or Last Option for Treatment of Hypothalamic Obesity? The Journal of clinical endocrinology and metabolism 2022 Jan ; 107:e426-e428 [PMID: 34331765] MUE2022
  8. Boguszewski MCS, Boguszewski CL, Chemaitilly W, Cohen LE, Gebauer J, Higham C, Hoffman AR, Polak M, Yuen KCJ, Alos N, Antal Z, Bidlingmaier M, Biller BMK, Brabant G, Choong CSY, Cianfarani S, Clayton PE, Coutant R, Cardoso-Demartini AA, Fernandez A, Grimberg A, Guðmundsson K, Guevara-Aguirre J, Ho KKY, Horikawa R, Isidori AM, Jørgensen JOL, Kamenicky P, Karavitaki N, Kopchick JJ, Lodish M, Luo X, McCormack AI, Meacham L, Melmed S, Mostoufi Moab S, Müller HL, Neggers SJCMM, Aguiar Oliveira MH, Ozono K, Pennisi PA, Popovic V, Radovick S, Savendahl L, Touraine P, van Santen HM, Johannsson G: Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement. European journal of endocrinology 2022, 186:P35-P52 [PMID: 35319491] BOG2022
  9. Sowithayasakul P, Boekhoff S, Bison B, Müller HL: Pregnancies after Childhood Craniopharyngioma: Results of KRANIOPHARYNGEOM 2000/2007 and Review of the Literature. Neuroendocrinology 2021, 111(1-2): 16 [PMID: 32074615] SOW2021a
  10. van Schaik J, Hoving EW, Müller HL, van Santen HM: Hypothalamic-Pituitary Outcome after Treatment for Childhood Craniopharyngioma. Frontiers of hormone research 2021, 54: 47 [PMID: 33965963] VSC2021
  11. Otte A, Müller HL: Childhood-onset Craniopharyngioma. The Journal of clinical endocrinology and metabolism 2021, 106:e3820-e3836 [PMID: 34086900] OTT2021
  12. Boekhoff S, Bison B, Genzel D, Eveslage M, Otte A, Friedrich C, Flitsch J, Müller HL: Cerebral Infarction in Childhood-Onset Craniopharyngioma Patients: Results of KRANIOPHARYNGEOM 2007. Frontiers in oncology 2021, 11: 698150 [PMID: 34336685] BOE2021
  13. Sowithayasakul P, Buschmann LK, Boekhoff S, Müller HL: Cardiac remodeling in patients with childhood-onset craniopharyngioma-results of HIT-Endo and KRANIOPHARYNGEOM 2000/2007. European journal of pediatrics 2021, 180: 1593 [PMID: 33459867] SOW2021
  14. Müller HL: The Diagnosis and Treatment of Craniopharyngioma. Neuroendocrinology 2020, 110(9-10): 753 [PMID: 31678973] MUE2020a
  15. Müller HL: Management of Hypothalamic Obesity. Endocrinology and metabolism clinics of North America 2020, 49: 533 [PMID: 32741487] MUE2020
  16. Müller HL: Reply to: Understanding treatment options in craniopharyngioma better. Nature reviews. Disease primers 2020, 6: 27 [PMID: 32300105] MUE2020
  17. Heinks K, De Schutter-Nüsse C, Boekhoff S, Bogusz A, Zhu J, Peng J, Müller HL: Periostin concentrations in childhood-onset craniopharyngioma patients. Journal of endocrinological investigation 2019, 42: 815 [PMID: 30474798] HEI2019a
  18. Müller HL: MANAGEMENT OF ENDOCRINE DISEASE: Childhood-onset craniopharyngioma: state of the art of care in 2018. European journal of endocrinology 2019, 180:R159-R174 [PMID: 30817319] MUE2019a
  19. Müller HL: The Diagnosis and Treatment of Craniopharyngiomas. Neuroendocrinology 2019,Epub ahead of print [PMID: 31678973] MUE2019a
  20. Daubenbüchel AM, Özyurt J, Boekhoff S, Warmuth-Metz M, Eveslage M, Müller HL: Eating behaviour and oxytocin in patients with childhood-onset craniopharyngioma and different grades of hypothalamic involvement. Pediatric obesity 2019, 14:e12527 [PMID: 31013553] DAU2019
  21. Bogusz A, Boekhoff S, Warmuth-Metz M, Calaminus G, Eveslage M, Müller HL: Posterior hypothalamus-sparing surgery improves outcome after childhood craniopharyngioma. Endocrine connections 2019, 8: 481 [PMID: 30925462] BOG2019
  22. Boekhoff S, Bison B, Eveslage M, Sowithayasakul P, Müller HL: Craniopharyngiomas presenting as incidentalomas: results of KRANIOPHARYNGEOM 2007. Pituitary 2019, 22: 532 [PMID: 31440945] BOE2019
  23. Müller HL, Merchant TE, Warmuth-Metz M, Martinez-Barbera JP, Puget S: Craniopharyngioma. Nature reviews. Disease primers 2019, 5: 75 [PMID: 31699993] MUE2019
  24. Eveslage M, Calaminus G, Warmuth-Metz M, Kortmann, RD, Pohl F, Timmermann B, Schuhmann MU, Flitsch J, Faldum A, Müller HL: Postoperative Lebensqualität bei Kindern und Jugendlichen mit Kraniopharyngeom. Dtsch Arztebl Int 2019, 116: 321 [URI: https://www.aerzteblatt.de/ archiv/ 206968/ Postoperative-Lebensqualitaet-bei-Kindern-und-Jugendlichen-mit-Kraniopharyngeom] EVE2019
  25. Müller HL: Hypothalamic involvement in craniopharyngioma-Implications for surgical, radiooncological, and molecularly targeted treatment strategies. Pediatric blood & cancer 2018, 65:e26936 [PMID: 29286573] MUE2018c
  26. Müller HL, Reichel J, Boekhoff S, Warmuth-Metz M, Eveslage M, Peng J, Flitsch J: Low concordance between surgical and radiological assessment of degree of resection and treatment-related hypothalamic damage: results of KRANIOPHARYNGEOM 2007. Pituitary 2018, 21: 371 [PMID: 29589225] MUE2018b
  27. Müller HL, Merks JHM, Geoerger B, Grill J, Hargrave D, Glade Bender J, Gururangan S, Navid F, Johnston M, Bachir J, Elze MC, Fürst-Recktenwald S: Integrated analysis of long-term growth and bone development in pediatric and adolescent patients receiving bevacizumab. Pediatric blood & cancer 2019, 66:e27487 [PMID: 30378286] MUE2018a
  28. Mehren A, Azyurt J, Zu Klampen P, Boekhoff S, Thiel CM, Müller HL: Self- and informant-rated apathy in patients with childhood-onset craniopharyngioma. Journal of neuro-oncology 2018, 140: 27 [PMID: 29971569] MEH2018
  29. Boekhoff S, Bogusz A, Sterkenburg AS, Eveslage M, Müller HL: Long-term Effects of Growth Hormone Replacement Therapy in Childhood-onset Craniopharyngioma: Results of the German Craniopharyngioma Registry (HIT-Endo). European journal of endocrinology 2018, 179: 331 [PMID: 30139824] BOE2018
  30. Bogusz A, Müler HL: Childhood-onset craniopharyngioma: latest insights into pathology, diagnostics, treatment, and follow-up. Expert review of neurotherapeutics 2018, 18: 793 [PMID: 30257123] BOG2018
  31. Mueller HL: Risk-adapted, long-term management in childhood-onset craniopharyngioma. Pituitary 2017, 20: 267 [PMID: 27604996] MUE2017b
  32. Mueller HL, Merchant TE, Puget S, Martinez-Barbera JP: New outlook on the diagnosis, treatment and follow-up of childhood-onset craniopharyngioma. Nature reviews. Endocrinology 2017, 13: 299 [PMID: 28155902] MUE2017a
  33. Hoffmann A, Azyurt J, Lohle K, Reichel J, Thiel CM, Mueller HL: First experiences with neuropsychological effects of oxytocin administration in childhood-onset craniopharyngioma. Endocrine 2017, 56: 175 [PMID: 28213803] HOF2017a
  34. Heinks K, Boekhoff S, Hoffmann A, Warmuth-Metz M, Eveslage M, Peng J, Calaminus G, Müller HL: Quality of life and growth after childhood craniopharyngioma: results of the multinational trial KRANIOPHARYNGEOM 2007. Endocrine 2018, 59: 364 [PMID: 29230635] HEI2017a
  35. Goschzik T, Gessi M, Dreschmann V, Gebhardt U, Wang L, Yamaguchi S, Wheeler DA, Lauriola L, Lau CC, Mueller HL, Pietsch T: Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma. Journal of neuropathology and experimental neurology 2017, 76: 126 [PMID: 28069929] GOS2017
  36. Mueller HL: Diagnosis, treatment, clinical course, and prognosis of childhood-onset craniopharyngioma patients. Minerva endocrinologica 2017, 42: 356 [PMID: 28181780] MUE2017
  37. Kilday JP, Caldarelli M, Massimi L, Chen RH, Lee YY, Liang ML, Parkes J, Naiker T, van Veelen ML, Michiels E, Mallucci C, Pettorini B, Meijer L, Dorfer C, Czech T, Diezi M, Schouten-van Meeteren AYN, Holm S, Gustavsson B, Benesch M, Mueller HL, Hoffmann A, Rutkowski S, Flitsch J, Escherich G, Grotzer M, Spoudeas HA, Azquikina K, Capra M, Jimenez-Guerra R, MacDonald P, Johnston DL, Dvir R, Constantini S, Kuo MF, Yang SH, Bartels U: Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN. Neuro-oncology 2017, 19: 1398 [PMID: 28499018] KIL2017
  38. Mueller HL: Craniopharyngioma and hypothalamic injury: latest insights into consequent eating disorders and obesity. Current opinion in endocrinology, diabetes, and obesity 2016, 23: 81 [PMID: 26574645] MUE2016a
  39. Hoffmann A, Warmuth-Metz M, Lohle K, Reichel J, Daubenbuechel AM, Sterkenburg AS, Mueller HL: Fusiform dilatation of the internal carotid artery in childhood-onset craniopharyngioma: multicenter study on incidence and long-term outcome. Pituitary 2016, 19: 422 [PMID: 27125511] HOF2016a
  40. Mueller HL: Risk-adapted treatment and follow-up management in childhood-onset craniopharyngioma. Expert review of neurotherapeutics 2016, 16: 535 [PMID: 26982163] MUE2016
  41. Hoffmann A, Brentrup A, Mueller HL: First report on spinal metastasis in childhood-onset craniopharyngioma. Journal of neuro-oncology 2016, 129: 193 [PMID: 27278607] HOF2016
  42. Sterkenburg AS, Hoffmann A, Reichel J, Lohle K, Eveslage M, Warmuth-Metz M, Mueller HL: Nuchal Skinfold Thickness: A Novel Parameter for Assessment of Body Composition in Childhood Craniopharyngioma. The Journal of clinical endocrinology and metabolism 2016, 101: 4922 [PMID: 27680877] STE2016
  43. Daubenbuechel AM, Hoffmann A, Eveslage M, Azyurt J, Lohle K, Reichel J, Thiel CM, Martens H, Geenen V, Mueller HL: Oxytocin in survivors of childhood-onset craniopharyngioma. Endocrine 2016, 54: 524 [PMID: 27585663] DAU2016
  44. Mueller HL: Craniopharyngioma: long-term consequences of a chronic disease. Expert review of neurotherapeutics 2015, 15: 1241 [PMID: 26523617] MUE2015a
  45. Mueller HL: Preoperative staging in childhood craniopharyngioma: standardization as a first step towards improved outcome. Endocrine 2016, 51: 1 [PMID: 26582066] MUE2015
  46. Hoffmann A, Warmth-Metz M, Gebhardt U, Pietsch T, Pohl F, Kortmann RD, Calaminus G, Müller HL: Childhood craniopharyngioma - changes of treatment strategies in the trials KRANIOPHARYNGEOM 2000/2007. Klinische Padiatrie 2014, 226: 161 [PMID: 24819386] HOF2014b
  47. Özyurt J, Thiel CM, Lorenzen A, Gebhardt U, Calaminus G, Warmuth-Metz M, Müller HL: Neuropsychological outcome in patients with childhood craniopharyngioma and hypothalamic involvement. The Journal of pediatrics 2014, 164: 876-881.e4 [PMID: 24507865] OZY2014a
  48. Hoffmann A, Gebhardt U, Sterkenburg A, Warmuth-Metz M, Müller HL: Diencephalic syndrome in childhood craniopharyngioma -Results of German multicentre studies on 485 long-term survivors of childhood craniopharyngioma. The Journal of clinical endocrinology and metabolism 2014,jc20141680 [PMID: 25077898] HOF2014a
  49. Ozyurt J, Lorenzen A, Gebhardt U, Warmuth-Metz M, Müller HL, Thiel CM: Remote effects of hypothalamic lesions in the prefrontal cortex of craniopharygioma patients. Neurobiology of learning and memory 2014, 111: 71 [PMID: 24662774] OZY2014
  50. Müller HL: Paediatrics: Surgical strategy and quality of life in craniopharyngioma. Nature reviews. Endocrinology 2013, 9: 447 [PMID: 23797818] MUE2013b
  51. Müller HL, Gebhardt U, Faldum A, Warmuth-Metz M, Pietsch T, Pohl F, Calaminus G, Sörensen N, Kraniopharyngeom 2000 Study Committee: Xanthogranuloma, Rathke's cyst, and childhood craniopharyngioma: results of prospective multinational studies of children and adolescents with rare sellar malformations. The Journal of clinical endocrinology and metabolism 2012, 97: 3935 [PMID: 22969141] MUE2012
  52. Kordes U, Flitsch J, Hagel C, Goebell E, Schwarz R, Herberhold T, von Bueren AO, Rutkowski S, Müller HL: Ectopic craniopharyngioma. Klin padiatr 2011, 223: 176 [PMID: 21462099] KOR2011a
  53. Müller HL: Consequences of craniopharyngioma surgery in children. J Clin Endocrinol Metab 2011, 96: 1981 [PMID: 21508127] MUE2011a
  54. Müller HL, Gebhardt U, Teske C, Faldum A, Zwiener I, Warmuth-Metz M, Pietsch T, Pohl F, Sörensen N, Calaminus G, the study committee of KRANIOPHARYNGEOM 2000: Post-operative hypothalamic lesions and obesity in childhood craniopharyngioma: results of the multinational prospective trial KRANIOPHARYNGEOM 2000 after 3-year follow-up. Eur J Endocrinol 2011, 165: 17 [PMID: 21490122] MUE2011
  55. Müller HL, Gebhardt U, Schröder S, Pohl F, Kortmann RD, Faldum A, Zwiener I, Warmuth-Metz M, Pietsch T, Calaminus G, Kolb R, Wiegand C, Sörensen N, study committee of KRANIOPHARYNGEOM 2000/2007: Analyses of treatment variables for patients with childhood craniopharyngioma--results of the multicenter prospective trial KRANIOPHARYNGEOM 2000 after three years of follow-up. Horm Res Paediatr 2010, 73: 175 [PMID: 20197669] MUE2010c
  56. Müller HL: Childhood craniopharyngioma: current controversies on management in diagnostics, treatment and follow-up. Expert Rev Neurother 2010, 10: 515 [PMID: 20367205] MUE2010b
  57. Müller HL: Increased daytime sleepiness in patients with childhood craniopharyngioma and hypothalamic tumor involvement: review of the literature and perspectives. nt J Endocrinol 2010, 2010, 519607 [PMID: 21234339] MUE2010
  58. Müller HL, Sörensen N: Kraniopharyngiom im Kindes- und Jugendalter. Interdisziplinäre Leitlinie der Deutschen Krebsgesellschaft und der Gesellschaft für Pädiatrische Onkologie und Hämatologie AWMF online 2008 [URI: http://www.awmf.org/ uploads/ tx_szleitlinien/ 025-026.pdf] MUE2008
  59. Müller HL: Childhood craniopharyngioma. Recent advances in diagnosis, treatment and follow-up. Horm Res 2008, 69: 193 [PMID: 18204266] MUE2008
  60. Roth CL, Hunneman DH, Gebhardt U, Stoffel-Wagner B, Reinehr T, Müller HL: Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma. Pediatr Res 2007, 61: 496 [PMID: 17515878] ROT2007
  61. Müller HL, Gebhardt U, Wessel V, Schröder S, Kolb R, Sörensen N, Maroske J, Hanisch E: First experiences with laparoscopic adjustable gastric banding (LAGB) in the treatment of patients with childhood craniopharyngioma and morbid obesity. Klin padiatr 2007, 219: 323-5. [PMID: 18050042] MUE2007
  62. Müller HL, Albanese A, Calaminus G, Hargrave D, Garré ML, Gebhardt U, Saran F, Sörensen N, Spoudeas HA: Consensus and perspectives on treatment strategies in childhood craniopharyngioma: results of a meeting of the Craniopharyngioma Study Group (SIOP), Genova, 2004. J Pediatr Endocrinol Metab 2006, 19 Suppl 1: 453 [PMID: 16700324] MUE2006b
  63. Müller HL, Gebhardt U, Pohl F, Flentje M, Emser A, Warmuth-Metz M, Kolb R, Calaminus G, Sörensen N: Relapse pattern after complete resection and early progression after incomplete resection of childhood craniopharyngioma. Klin Pädiatr 2006, 218: 315-20. [PMID: 17080333] MUE2006a
  64. Müller H: Warum brauchen manche Hirntumorpatienten Hormone, obwohl ihre Drüsen gesund sind? WIR Informationsschrift der Aktion für krebskranke Kinder e.V. (Bonn) 2006, 2: 12 [URI: http://www.kinderkrebsstiftung.de/ fileadmin/ KKS/ files/ zeitschriftWIR/ 2006_2/ hormone.pdf] MUE2006

CNS tumours in general

Literature on CNS tumours in general

Pubmed

  1. Jazmati D, Steinmeier T, Ahamd Khalil D, Frisch S, Peters S, Schulze Schleithoff S, Bäumer C, Rutkowski S, Frühwald MC, Blase C, Tippelt S, Timmermann B: Feasibility of Proton Beam Therapy for Infants with Brain Tumours: Experiences from the Prospective KiProReg Registry Study. Clinical oncology 2021, 33:e295-e304 [PMID: 33820696] JAZ2021
  2. Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM: DNA methylation-based classification of central nervous system tumours. Nature 2018, 555: 469 [PMID: 29539639] CAP2018
  3. Ardon H, De Vleeschouwer S, Van Calenbergh F, Claes L, Kramm CM, Rutkowski S, Wolff JE, Van Gool SW: Adjuvant dendritic cell-based tumour vaccination for children with malignant brain tumours. Pediatric blood & cancer 2010, 54: 519 [PMID: 19852061] ARD2010
  4. Benesch M, Siegler N, Hoff K, Lassay L, Kropshofer G, Müller H, Sommer C, Rutkowski S, Fleischhack G, Urban C: Safety and toxicity of intrathecal liposomal cytarabine (Depocyte) in children and adolescents with recurrent or refractory brain tumors: a multi-institutional retrospective study. Anti-cancer drugs 2009, 20: 794 [PMID: 19617818] BEN2009a
  5. Rutkowski S, Riehle E: Access to employment and economic independence in cerebral palsy. Physical medicine and rehabilitation clinics of North America 2009, 20: 535 [PMID: 19643352] RUT2009
  6. Rutkowski S: Timely identification of suspected paediatric CNS tumours. The lancet oncology 2007, 8: 664 [PMID: 17679075] RUT2007