What are the different types of stem cell transplantation?
Depending on the type of donor, a distinction is made between allogeneic and autologous stem cell transplantation. In this text, you can find out about the process of these two forms of transplantation and their possible applications in paediatric cancer medicine.
Author: Dr. med. Gesche Riabowol née Tallen, Dr. med. Jörn Kühl, Editor: Maria Yiallouros, Reviewer: PD Dr. med. S. Voigt, English Translation: Dr. med. Gesche Riabowol (nee Tallen), Last modification: 2024/04/29 https://kinderkrebsinfo.de/doi/e4967
If, after a thorough examination of the overall situation, a haematopoietic stem cell transplantation (HSCT) proves to be indicated, the next step is to select the form that is most feasible for your child with regards to efficacy and safety. Also, a matching stem cell donor is required for certain types of HSCT.
Basically, there are two major types of HSCT depending on the type of donor:
In autologous stem cell transplantation, the patient receives his/her own blood stem cells, which were previously collected from him/her. In allogeneic stem cell transplantation, the patient receives blood stem cells from a donor. A special form of allogeneic stem cell transplantation is syngeneic stem cell transplantation, in which the patient receives blood stem cells from an identical twin.
The different forms of blood stem cell transplantation are explained in more detail on the following pages.
